Testing in vitro

EPO has a broad collection of cell lines available, including:

Human tumour cell lines
Murine tumour cell lines
Rat tumour cell lines

Genetically modified cell lines for expression of:

Estrogen receptor
GFP
Luciferase

EPO additionally offers to establish customer derived cells.

Cytotoxicity of test compounds is determined to estimate the potential for further in vivo evaluation. Following cytotoxicity parameters are determined routinely:

Growth inhibition
Induction of apoptosis
Senescence

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