TARGET IDENTIFICATION
AND VALIDATION large panels of tumor models corresponding repositories of tumor material
(OTC, snap frozen, FFPE, DNA, RNA) extensive data about histology, genetic profile
and drug sensitivity

LEAD
OPTIMIZATION tumor models with defined target expression for screening and comparison with standards implementation of transgenic techniques PK/PD/Tox studies

TRANSLATIONAL
RESEARCH extensively characterized patient derived xenografts
for applied studies (preclinical phase II) implementation of individualized therapy experimental imaging