13th – 16th of November 2022

35. Deutscher Krebskongress Berlin (35th German Cancer Congress Berlin)

EPO scientists presented new models for preclinical translational cancer research in two lectures at the plenary session "Translational Oncology: Innovative Tumor Models - Translation into the Clinic or Remaining in the Laboratory?" Our colleague Dr. Simone Rhein presented new "Humanized tumor models for immuno-oncology research" and Dr. Jens Hoffmann reported on "New approaches for the use of patient-derived xenografts in translational oncology".

In the poster sessions of the congress, further EPO researchers presented the development of patient-derived xenograft (PDX) models from high-risk childhood cancers for preclinical evaluation of novel therapeutics, presented new data on HLA-typing of PDX models for improved immune oncology applications and on thorough characterization of newly established PDX models derived from peritoneal metastases of colorectal cancer (all published in the special issue of Oncol Res Treatment, Vol. 45, Suppl. 3, 2022).