Newsletter March 2025
AACR 2025 | Chicago
Join EPO for a Dinner Reception at the River North Bistro
Dear Colleague,
Are you looking forward to attending AACR 2025 and experiencing the vibrant heart of downtown Chicago?
We’re excited to invite you to a special evening reception at River North Bistro on Sunday, April 27, 6:00pm - 9:00pm, just steps away from Chicago’s iconic Magnificent Mile.
Enjoy a relaxed atmosphere with handcrafted cocktails and a selection of delicious bites while catching up with colleagues and friends. We’ll also share the latest updates from EPO and how our innovative preclinical models are advancing oncology drug development.
Secure your spot by signing up with Turn on Javascript!.
We’re also thrilled to showcase our latest scientific advancements at AACR 2025. Visit our poster and talk sessions to discuss your drug development strategies with our experts and learn how EPO’s preclinical tumor models can accelerate your oncology research.
We look forward to seeing you in Chicago!
Best regards,
Jens Hoffmann (CEO), Wolfgang Walther (CSO), Antje Wengner (CSO)
EPO Berlin-Buch
Talks
Triple negative breast cancer (TNBC) PDX models for preclinical investigation of novel therapies
Speaker: Jens Hoffmann (presenting on behalf of Diana Behrens)
Session Date & Time: April 28, 2025 | 2:30 PM – 4:30 PM
Session Type: Minisymposium
Session Category: Tumor Biology
Session Title: Cancer Models: Mechanisms and Therapies
Abstract Number: 3823
Abstract
Molecular profiles and drug response of ITCC-P4 patient-derived xenograft pediatric cancer models for target identification and prediction of targeted therapies
Speaker: Dennis Gürgen
Session Date & Time: April 27, 2025 | 3:00 PM – 5:00 PM
Session Type: Minisymposium
Session Category: Tumor Biology
Session Title: Advancing the Science of Childhood Cancers: From Bench to Bedside
Abstract Number: 1202
Abstract
Posters
The ITCC-P4 consortium: Deep molecular characterization of pediatric cancer xenograft (PDX) models enable prediction of novel personalized combination treatment options for patients with childhood cancer
Presenter: Dennis Gürgen
Session Date & Time: April 27, 2025 | 2:00 PM – 5:00 PM
Session Category: Clinical Research
Session Title: Targeted Therapies and Combinations 1
Location: Poster Section 34 | Board #28
Abstract Number: 840
Abstract
Long-term humanization of NOG mice and next-generation NOG strains to induce lineage-specific differentiation of immune cells for assessment of novel immune cell therapies, check point inhibitors, and immune cell engagers for translational immuno-oncology research.
Presenter: Maria Stecklum
Session Date & Time: April 30, 2025 | 9:00 AM – 12:00 PM
Session Category: Immunology
Session Title: Novel Animal Models / Tumor Antigenicity/Processing and Presentation
Location: Poster Section 37 | Board #4
Abstract Number: 7228
Abstract